HUMAN SEMINAL TRYPSIN INHIBITORS

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Competition among trypsin inhibitors.

The experiments presented in this paper were designed to elucidate the kinetics of action of three protein inhibitors (from pancreas, soy bean, and egg white) on trypsin, and to discover how the inhibition by these substances was related to the action of diisopropyl fluorophosphate (DFP), mercuric chloride, and calcium salts on trypsin. The most, detailed work on the protein inhibitors of tryps...

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Significance of Soya Trypsin Inhibitors

Although recent evidence clearly indicates that trypsin inhibitors (TO and low protein digestibility are the major factors responsible for the pancreatic hypertrophic and growth inhibitory effects of raw soybeans, there was uncertainty regarding the biological threshold level of TI at which these biological effects occur. To obtain such data, dehulled defatted flakes (10% dietary protein) conta...

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Low Trypsin Inhibitors and Chymotrypsin Inhibitors in Winged Bean Mutants

In present studies several attempts have been made to reduce the amount of trypsin and chymotrypsin inhibitors in winged bean (Psophocarpus tetragonolobus) mutants developed through induced mutation. The low seed TI (trypsin inhibitor) lines comprised long pod-5 and long pod-2 mutant lines. The low tuber TI feature could be noted in the mutant population. Such lines were long pod-5, large leaf/...

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Two trypsin inhibitors from porcine pancreatic juice.

Two trypsin inhibitors of the Kazal type have been isolated from porcine pancreatic juice. They have been prepared in 65% yield by gel titration on Sephadex G-75 at pH 8.1 in the presence of lo-*M diisopropyl phosphofluoridate, tiltration through diethylaminoethyl cellulose at pH 9, and equilibrium chromatography on sulfoethyl Sephadex at pH 5.4. The major component, Porcine Inhibitor I, has a ...

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The reactive site of trypsin inhibitors.

Virgin soybean trypsin inhibitor has 1 NHp-terminal aspartic acid or asparagine residue and no COOH-terminal residues that can be released by carboxypeptidase B. Upon incubation with 1 mole % of trypsin for 24 hours at pH 3.75, virgin inhibitor is converted to a modified inhibitor which has 2 NH2 terminals aspartic acid or asparagine and isoleucine. Approximately 1 mole of arginine is released ...

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ژورنال

عنوان ژورنال: Reproduction

سال: 1972

ISSN: 1470-1626,1741-7899

DOI: 10.1530/jrf.0.0290163